FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Cdc37, InR
FlyBase ID
FBig0000116796
Interaction Network
Interactions Browser links
Cdc37 network
InR network
Reported Interactions
FBrf0240343-2.PLA
Reference
Huang and Wang, 2018
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
Cdc37 

Cdc37

neutral component

Myc tag

Cdc37 

Cdc37

neutral component

Myc tag

Cdc37 

Cdc37

neutral component

Myc tag

InR 

InR

neutral component

HA tag

InR 
InR 

InR

neutral component

HA tag

InR 

InR

neutral component

HA tag

InR 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
InR 
intracellular domain
sufficient binding region
aa 1372-2144

coordinates relative to InR-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was live S2 cells; proteins produced from transfected constructs.

(Huang and Wang, 2018)
FBrf0240343-5.BiFC.FM
Reference
Huang and Wang, 2018
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
Cdc37 

Cdc37

bait

YFP tag, N-terminal fragment

InR 

InR

prey

YFP tag, C-terminal fragment

InR 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
InR 
intracellular domain
sufficient binding region
aa 1372-2144

coordinates relative to InR-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was live S2 cells; proteins produced from transfected constructs.

(Huang and Wang, 2018)
FBrf0240343-8.BiFC.FM
Reference
Huang and Wang, 2018
Description
physical association
Assay
Collection
Source/Stage
neuroblast / larval stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Cdc37 

Cdc37

bait

YFP tag, N-terminal fragment

InR 

InR

prey

YFP tag, C-terminal fragment

InR 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
InR 
intracellular domain
sufficient binding region
aa 1372-2144

coordinates relative to InR-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was larvae of transgenic fly line; bait produced from tagged transgenic construct; prey produced from tagged transgenic construct.

(Huang and Wang, 2018)
External Crossreferences and Linkouts ( 0 )
References (1)