FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Su(var)205, Hsp70
FlyBase ID
FBig0000119825
Interaction Network
Interactions Browser links
Su(var)205 network
Hsp70 network
Reported Interactions
FBrf0209129-14a.EMSA.A
Reference
Piacentini et al., 2009
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Su(var)205 

HP1a

bait

GST tag

Su(var)205 
Su(var)205 
Su(var)205 
Hsp70 

Hsp70

prey

[32]P label

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Su(var)205 
chromo domain
necessary binding region
aa 1-94
Su(var)205 
chromo domain
sufficient binding region
aa 1-150
Su(var)205 
interaction domain
sufficient binding region
aa 1-95,152-206

construct with an internal hinge domain deleted

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey produced and labeled by in vitro transcription.

(Piacentini et al., 2009)
FBrf0209129-2a.XL.A
Reference
Piacentini et al., 2009
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Hsp70 

Hsp70

bait

[32]P label

Su(var)205 

HP1a

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced and labeled by in vitro transcription; prey produced as a recombinant fusion protein in bacterial system.

(Piacentini et al., 2009)
FBrf0209129-8a.coIP.PE
Reference
Piacentini et al., 2009
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
Su(var)205 

HP1a

bait
Hsp70 

Hsp70

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from endogenous gene; prey produced from endogenous gene.

(Piacentini et al., 2009)
External Crossreferences and Linkouts ( 0 )
References (1)