FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Dyrk2, Snr1
FlyBase ID
FBig0000119863
Interaction Network
Interactions Browser links
Dyrk2 network
Snr1 network
Reported Interactions
FBrf0192426-1.Y2H
Reference
Kinstrie et al., 2006
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Dyrk2 

dDyrk2

bait

fused to GAL4 DNA-binding domain

Snr1 

Snr1

prey

fused to GAL4 activation domain

Snr1 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Snr1 
interaction domain
sufficient binding region
aa 94-370
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Two-hybrid system: yeast GAL4-BD/GAL4-AD

(Kinstrie et al., 2006)

Source was yeast cell line; bait produced as transgenic fusion protein; prey produced as transgenic fusion protein (prey from embryo cDNA expression library).

(Kinstrie et al., 2006)
FBrf0192426-13.ENZ.A
Reference
Description
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Dyrk2 

dDyrk2

enzyme

FLAG tag

Dyrk2 
Dyrk2 
Dyrk2 

dDyrk2

enzyme

FLAG tag

Snr1 

Snr1

enzyme target

GST tag, P[32] label

Snr1 

Snr1

enzyme target

GST tag, P[32] label

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction
FBrf0192426-15.ENZ.WB
Reference
Description
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Dyrk2 

dDyrk2

enzyme

FLAG tag

Dyrk2 

dDyrk2

enzyme

FLAG tag

Dyrk2 
Snr1 

Snr1

enzyme target

GST tag

Snr1 

Snr1

enzyme target

GST tag

Snr1 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction
FBrf0192426-3.Y2H
Reference
Kinstrie et al., 2006
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Dyrk2 

dDyrk2

bait

fused to GAL4 DNA-binding domain

Dyrk2 
Snr1 

Snr1

prey

fused to GAL4 activation domain

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Dyrk2 
C-terminal domain
sufficient binding region
unspecified
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was yeast cell line; bait produced as transgenic fusion protein; prey produced as transgenic fusion protein (prey was previously cloned reagent).

(Kinstrie et al., 2006)

Two-hybrid system: yeast GAL4-BD/GAL4-AD

(Kinstrie et al., 2006)
FBrf0192426-5.coIP.WB
Reference
Kinstrie et al., 2006
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Dyrk2 

dDyrk2

bait

FLAG tag

Dyrk2 
Snr1 

Snr1

prey

HA tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Dyrk2 
C-terminal domain
necessary binding region
unspecified
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of Sf9 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Kinstrie et al., 2006)
FBrf0192426-6.coIP.WB
Reference
Kinstrie et al., 2006
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Snr1 

Snr1

bait

HA tag

Dyrk2 

dDyrk2

prey

FLAG tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of Sf9 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Kinstrie et al., 2006)
External Crossreferences and Linkouts ( 0 )
References (1)