smi35A, dDYRK2, smell impaired 35A, DYRK, BG:DS01523.3
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Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.44
Stop-codon suppression (UGA) postulated; FBrf0216884.
gene_with_stop_codon_read_through ; SO:0000697
Gene model reviewed during 5.48
Phosphorylated on serine/threonine residues.
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GBrowse - Visual display of RNA-Seq signals
View Dmel\Dyrk2 in GBrowse 22-50
2-50
2-45.9
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Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: smi35A CG4551
The relationship between the "smi35A" mutation and the "DYRK2" transcription unit is unclear; the "smi35A" mutation was isolated in a P-element mutagenesis screen as a mutation with an olfaction defective phenotype and "DYRK2" was considered to be the protein product of "smi35A" based on the location of the P-element (P{lacW}smi35Ak11509) in the mutant line. However, the smell-impaired phenotype can be lost in P{lacW}smi35Ak11509 flies and P{lacW}smi35Ak11509 embryos show normal expression and tyrosine-phosphorylation of "DYRK2". Further analysis is therefore needed to demonstrate that the "smi35A" phenotype is attributable to the "DYRK2" gene.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
Area matching Drosophila ESTs AA440852 and AA541034.
Identified during a screen for olfactory mutants.