FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
DZIP1, Cby
FlyBase ID
FBig0000120229
Interaction Network
Interactions Browser links
DZIP1 network
Cby network
Reported Interactions
FBrf0244294-2.coIP.WB
Reference
Lapart et al., 2019
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
DZIP1 

Dzip1

bait

HA or GFP tag

Cby 

Cby

prey

GFP or HA tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of COS-7 or HEK293 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Lapart et al., 2019)
FBrf0247748-6.PD.WB
Reference
Wu et al., 2020
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
DZIP1 

DZIP1

bait

GST tag

DZIP1 
DZIP1 
Cby 

CBY

prey

His tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
DZIP1 
N-terminal domain
sufficient binding region
aa 1-293

coordinates relative to DZIP1-PA

DZIP1 
C-terminal domain
sufficient binding region
aa 294-737

coordinates relative to DZIP1-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey produced as a recombinant fusion protein in bacterial system.

(Wu et al., 2020)
FBrf0247748-7.coIP.WB
Reference
Wu et al., 2020
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
DZIP1 

DZIP1

bait

GFP tag

Cby 

CBY

prey

HA tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Wu et al., 2020)
External Crossreferences and Linkouts ( 0 )
References (2)