FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Irp-1A, SdhB
FlyBase ID
FBig0000120331
Interaction Network
Interactions Browser links
Irp-1A network
SdhB network
Reported Interactions
FBrf0244135-2.coIP.PCR
Reference
Huynh et al., 2019
Description
physical association
Assay
Collection
Source/Stage
organism / late third instar larval stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Irp-1A 

IRP1A

bait

FLAG tag

Irp-1A 
Irp-1A 
SdhB 

SdhB

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Irp-1A 
Fe-S cluster binding domain residue 450
mutation increasing interaction
aa 450

C450S, coordinates relative to Irp-1A-PA

Irp-1A 
interaction domain residues 549,554,793
mutation disrupting interaction
aa 549,554,793

R549Q,R554Q,R793Q, coordinates relative to Irp-1A-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was larvae; bait produced from tagged knock-in construct; prey produced from endogenous gene.

(Huynh et al., 2019)
External Crossreferences and Linkouts ( 0 )
References (1)