FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Sirt1, Atg8a
FlyBase ID
FBig0000120464
Interaction Network
Interactions Browser links
Sirt1 network
Atg8a network
Reported Interactions
FBrf0245785-3.coIP.WB
Reference
Jacomin et al., 2020
Description
physical association
Assay
Collection
Source/Stage
organism / early third instar larval stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Sirt1 

Sir2

bait

Myc tag

Atg8a 

Atg8a

prey

GFP tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was larvae of transgenic fly line; bait produced from tagged transgenic construct; prey produced from tagged transgenic construct.

(Jacomin et al., 2020)
FBrf0245785-4.PD.WB
Reference
Jacomin et al., 2020
Description
physical association
Assay
Collection
Source/Stage
organism / early third instar larval stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Atg8a 

Atg8a

bait

GST tag

Atg8a 
Sirt1 

Sir2

prey

Myc tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Atg8a 
LIR docking site residue 49
mutation decreasing interaction
aa 49

Y49A, coordinates relative to Atg8a-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey derived from transgenic larval extract.

(Jacomin et al., 2020)
External Crossreferences and Linkouts ( 0 )
References (1)