FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
TBPH, Syx1A
FlyBase ID
FBig0000120585
Interaction Network
Interactions Browser links
TBPH network
Syx1A network
Reported Interactions
FBrf0246089-2.coIP.PCR
Reference
Romano et al., 2020
Description
physical association
Assay
Collection
Source/Stage
head / adult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
TBPH 

TBPH

bait

FLAG tag

TBPH 
Syx1A 

syntaxin

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
TBPH 
RNA-binding domain
mutation disrupting interaction
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Positive control.

(Romano et al., 2020)

Source was adult heads; bait produced from tagged transgenic construct; prey produced from endogenous gene.

(Romano et al., 2020)
FBrf0264006-2.coIP.PCR
Reference
Gbadamosi et al., 2025
Description
physical association
Assay
Collection
Source/Stage
adult head / adult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
TBPH 

TDP-43

bait

FLAG tag

TBPH 
Syx1A 

Syx1A

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
TBPH 
RNA binding domain residues 147 and 149
mutation decreasing interaction
aa 147 and 149

F147L, F149L

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

positive control

(Gbadamosi et al., 2025)

Source was adult heads; bait produced from tagged transgenic construct; prey produced from endogenous gene.

(Gbadamosi et al., 2025)
External Crossreferences and Linkouts ( 0 )
References (2)