FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
Interacting Genes
FlyBase ID
FBig0000121034
Interaction Network
Interactions Browser links
CoRest network
ttk network
Reported Interactions
FBrf0180423-1.Y2H
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note

dCoRest

bait

fused to LexA

ttk 

Ttk88

prey

from Matchmaker Drosophila cDNA library

ttk 
ttk 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
interaction domain
sufficient binding region
aa 64-273

coordinates relative to CoRest-PA

ttk 
interaction domain
sufficient binding region
aa 432-811

coordinates relative to ttk-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was yeast cell line; bait produced as transgenic fusion protein; prey produced as transgenic fusion protein (prey from embryo cDNA expression library).

FBrf0180423-2.coIP.WB
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note

dCR

bait
ttk 

Ttk88

prey

HA-tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was S2 cells; bait produced from endogenous gene; prey produced from transfected construct.

FBrf0180423-3.coIP.WB
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
ttk 

Ttk88

bait

HA-tag

dCR

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was S2 cells; bait produced from transfected construct; prey produced from endogenous gene.

FBrf0180423-5.coIP.WB
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note

dCR

bait
ttk 

Ttk69

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

CoRest interaction with the ttk 67kDa isoform detected with an antibody specific to the 67kDa isoform.

Source was S2 cells; bait produced from endogenous gene; prey produced from transfected construct.

External Crossreferences and Linkouts ( 0 )
References (1)