FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Cyt-c-p, Hsap\UQCRC1
FlyBase ID
FBig0000121485
Interaction Network
Interactions Browser links
Cyt-c-p network
Hsap\UQCRC1 network
Reported Interactions
FBrf0251393-2.PLA.FM
Reference
Hung et al., 2021
Description
physical association
Assay
Collection
Source/Stage
photoreceptor / adult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Cyt-c-p 

cyt-c

bait

anti-mouse PLA probe

Hsap\UQCRC1 

UQCRC1

prey

V5 tag; anti-rabbit PLA probe

Hsap\UQCRC1 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Hsap\UQCRC1 
Parkinsons disease associated mutation residue 314
mutation decreasing interaction
aa 314

Y314S

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was photoreceptors of a transgenic fly line; bait produced from endogenous gene; prey produced from transgenic construct.

(Hung et al., 2021)

Within the context of a UQCR-C1 RNAi transgenic line.

(Hung et al., 2021)
FBrf0251393-4.coIP.WB
Reference
Hung et al., 2021
Description
physical association
Assay
Collection
Source/Stage
adult head / adult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Hsap\UQCRC1 

UQCRC1

bait

V5 tag

Hsap\UQCRC1 
Cyt-c-p 

cyt-c

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Hsap\UQCRC1 
Parkinsons disease associated mutation residue 314
mutation decreasing interaction
aa 314

Y314S

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was adult heads of transgenic fly line; bait produced from tagged transgenic construct; prey produced from endogenous gene.

(Hung et al., 2021)

Within the context of a UQCR-C1 RNAi transgenic line.

(Hung et al., 2021)
External Crossreferences and Linkouts ( 0 )
References (1)