FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
AGO1, Sec61β
FlyBase ID
FBig0000121720
Interaction Network
Interactions Browser links
AGO1 network
Sec61β network
Reported Interactions
FBrf0253135-15.CL.FM
Reference
Gao et al., 2022
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
AGO1 

AGO1

bait

RA fluorescence-capable domain

Sec61β 

Sec61β

prey

GB core domain

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was live, human U2OS cells; bait produced from tagged transgenic construct; prey produced from tagged transgenic construct.

(Gao et al., 2022)

Interaction detected by the ddFP system; RA is a quenched chromophore in a monomeric state, GB is able to increase fluorescence of RA when a heterodimer is formed.

(Gao et al., 2022)
External Crossreferences and Linkouts ( 0 )
References (1)