FB2026_02 , released June 18, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Roc2, Cul5
FlyBase ID
FBig0000121721
Interaction Network
Interactions Browser links
Roc2 network
Cul5 network
Reported Interactions
FBrf0180504-7.coIP.MS
Reference
Donaldson et al., 2004
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Roc2 

Roc2

bait

Flag-tag

Cul5 

CUL-5

prey

11 unique peptides identified

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was embryo lysates; bait produced from transgenic construct; prey produced from endogenous gene.

(Donaldson et al., 2004)
FBrf0205823-10.coIP.WB
Reference
Reynolds et al., 2008
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
Roc2 

ROC2

bait

V5 tag

Cul5 

Cul5

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from endogenous gene.

(Reynolds et al., 2008)
FBrf0205823-6.coIP.WB
Reference
Reynolds et al., 2008
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Roc2 

ROC2

bait

FLAG tag

Cul5 

Cul5

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was embryos of transgenic fly line; bait produced from tagged transgenic construct; prey produced from endogenous gene.

(Reynolds et al., 2008)
External Crossreferences and Linkouts ( 0 )
References (2)