FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
eIF4E1, SERCA
FlyBase ID
FBig0000121780
Interaction Network
Interactions Browser links
eIF4E1 network
SERCA network
Reported Interactions
FBrf0253516-2.Y2H
Reference
Santalla et al., 2022
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
eIF4E1 

eIF4E-1

bait

fused to GAL4 DNA-binding domain

SERCA 

SERCA

prey

fused to GAL4 activation domain

SERCA 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
SERCA 
interaction domain residues 1-250
sufficient binding region
aa 1-250
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Two-hybrid system: yeast GAL4-BD/VP16-AD

(Santalla et al., 2022)

Source was yeast cell line; bait produced as transgenic fusion protein; prey produced as transgenic fusion protein (prey was previously cloned reagent).

(Santalla et al., 2022)
External Crossreferences and Linkouts ( 0 )
References (1)