FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Wdr24, Sesn
FlyBase ID
FBig0000121865
Interaction Network
Interactions Browser links
Wdr24 network
Sesn network
Reported Interactions
FBrf0254204-2.coIP.WB
Reference
Gu et al., 2022
Description
physical association
Assay
Collection
Source/Stage
fat body / third instar larval stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Wdr24 

WDR24

bait

Myc tag

Sesn 

Sestrin

prey
Sesn 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Sesn 
leucine binding residue 431
mutation increasing interaction
aa 431

L431E

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Larvae fed a diet deficient in Leucine increases interaction between Wdr24 and Sesn.

(Gu et al., 2022)

Source was embryos of transgenic fly line; bait produced from tagged transgenic construct; prey produced from endogenous gene.

(Gu et al., 2022)
External Crossreferences and Linkouts ( 0 )
References (1)