FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Duox, ATP8B
FlyBase ID
FBig0000123213
Interaction Network
Interactions Browser links
Duox network
ATP8B network
Reported Interactions
FBrf0259381-7.PD.WB
Reference
Liang et al., 2024
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
ATP8B 

ATP8B

bait

biotin label

ATP8B 
ATP8B 
Duox 

Duox

prey

FLAG tag

Duox 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Duox 
C-terminal domain
sufficient binding region
aa 1219-1517

coordinates relative to Duox-PC

ATP8B 
interaction domain
necessary binding region
nt 50-122
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait and prey produced from transfected constructs.

(Liang et al., 2024)
FBrf0259381-9.coIP.PCR
Reference
Liang et al., 2024
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
Duox 

Duox

bait

FLAG tag

Duox 
ATP8B 

ATP8B

prey
ATP8B 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Duox 
NAD-BD domain
sufficient binding region
aa 1362-1517

coordinates relative to Duox-PC

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from tagged transgenic construct; prey produced from endogenous gene.

(Liang et al., 2024)
External Crossreferences and Linkouts ( 0 )
References (1)