FB2026_03 , released September 17, 2026
Physical Interaction report
Open Close
General Information
Interaction Type
physical association
Interacting Genes
Dg, Nrx-1
FlyBase ID
FBig0000123416
Interaction Network
Interactions Browser links
Dg network
Nrx-1 network
Reported Interactions
FBrf0260973-1.coIP.WB
Reference
Zhao et al., 2024
Description
physical association
Assay
Collection
Source/Stage
hypodermal muscle of A1-7 / third instar larval stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Dg 

Dg

bait

HA tag

Nrx-1 

DNRX

prey

GFP tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was body wall muscle of transgenic fly line; bait and prey produced from tagged transgenic constructs.

(Zhao et al., 2024)
FBrf0260973-2.coIP.WB
Reference
Zhao et al., 2024
Description
physical association
Assay
Collection
Source/Stage
hypodermal muscle of A1-7 / third instar larval stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Nrx-1 

DNRX

bait

GFP tag

Dg 

Dg

prey

HA tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was body wall muscle of transgenic fly line; bait and prey produced from tagged transgenic constructs.

(Zhao et al., 2024)
FBrf0260973-3.coIP.WB
Reference
Zhao et al., 2024
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
Dg 

Dg

bait

GFP tag

Nrx-1 

DNRX

prey

mCherry tag

Nrx-1 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Nrx-1 
extracellular domain
necessary binding region
aa 1-1693

coordinates relative to AA-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Zhao et al., 2024)
FBrf0260973-4.coIP.WB
Reference
Zhao et al., 2024
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Dg 

Dg

bait

GFP tag

Nrx-1 

DNRX

prey

mCherry tag

Nrx-1 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Nrx-1 
extracellular domain
necessary binding region
aa 1-1693

coordinates relative to AA-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of HEK293T cell line; bait produced from transfected construct; prey produced from transfected construct.

(Zhao et al., 2024)
FBrf0260973-5.coIP.WB
Reference
Zhao et al., 2024
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
Nrx-1 

DNRX

bait

mCherry tag

Dg 

Dg

prey

GFP tag

Dg 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Dg 
extracellular domain
necessary binding region
aa 28-1051

coordinates relative to Dg-PC

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Zhao et al., 2024)
FBrf0260973-6.coIP.WB
Reference
Zhao et al., 2024
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Nrx-1 

DNRX

bait

mCherry tag

Dg 

Dg

prey

GFP tag

Dg 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Dg 
extracellular domain
necessary binding region
aa 28-1051

coordinates relative to Dg-PC

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of HEK293T cell line; bait produced from transfected construct; prey produced from transfected construct.

(Zhao et al., 2024)
External Crossreferences and Linkouts ( 0 )
References (1)