FB2026_03 , released September 17, 2026
Physical Interaction report
Open Close
General Information
Interaction Type
physical association
Interacting Genes
Eph, Vav
FlyBase ID
FBig0000123985
Interaction Network
Interactions Browser links
Eph network
Vav network
Reported Interactions
FBrf0263961-1.coIP.WB
Reference
Kamiyama et al., 2025
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
Eph 

Eph

bait

FC tag

Eph 
Vav 

Vav

prey

FLAG tag

Vav 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Eph 
intracellular domain tyrosine residues
mutation disrupting interaction
aa 651, 667, 673, 691

Y651F,Y667F,Y673F,Y691F; within the context of aa 629-1047.

Vav 
SH2 domain
necessary binding region
aa 622-706
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Kamiyama et al., 2025)
External Crossreferences and Linkouts ( 0 )
References (1)