Tchurikov, N.A., Gerasimova, T.I., Johnson, T.K., Barbakar, N.I., Kenzior, A.L., Georgiev, G.P. (1989). Mobile elements and transposition events in the cut locus of Drosophila melanogaster. Mol. Gen. Genet. 219(): 241--248.
FlyBase ID
FBrf0050561
Publication Type
Research paper
Abstract
We have cloned from the Oregon R strain of Drosophila melanogaster a 240 kb segment of DNA that contains the cut (ct) locus, and characterized the region for the presence of repetitive elements. Within this region at least five copies of the suffix element were detected, as well as several putatively novel mobile elements. A number of mutations obtained from the unstable ctMR2 strain and its derivatives were mapped within the cut locus. Comparison between parental and daughter strains indicates that frequently two or more independent transposition events involving the cut locus occur simultaneously within a single germ cell, thus providing a molecular basis for the transposition explosion phenomenon.
