Wheeler, D.A., Kyriacou, C.P., Greenacre, N.L., Yu, Q., Rutila, J.E., Rosbash, M., Hall, J.C. (1991). Molecular transfer of a species-specific behavior from Drosophila simulans to Drosophila melanogaster.  Science 251(): 1082--1085.

FBrf0055055

Research paper

Drosophila males modulate the interpulse intervals produced during their courtship songs. These song cycles, which are altered by mutations in the clock gene period, exhibit a species-specific variation that facilitates mating. We have used chimeric period gene constructs from Drosophila melanogaster and Drosophila simulans in germline transformation experiments to map the genetic control of their song rhythm difference to a small segment of the amino acid encoding information within this gene.