Renault, S., de Groote, F., Picard, G. (1993). Despite its high representation in extrachromosomal circular DNAs from Drosophila embryos, the dodecasatellite does not allow autonomous replication in cultured cells. Biol. Cell 79(1): 51--54.
FlyBase ID
FBrf0068649
Publication Type
Research paper
Abstract
The dodecasatellite is a 11/12 bp tandemly repeated sequence which is overrepresented, with regard to its genomic representation, in extrachromosomal circular DNAs from D melanogaster embryos. Here we show that a bacterial plasmid carrying a cluster of dodecasatellite is not able to replicate efficiently in cultured cells. This observation does not support the hypothesis that the overrepresentation results from an autonomous replication of dodecasatellite circular DNA molecules.
