Zakharenko, L.P., Zakharov, I.K. (1998). [Ethanol suppresses recombination in somatic cells of -irradiated larvae of Drosophila melanogaster.]  Genetika, Moscow 34(3): 364--367.

FBrf0103070

Research paper

Raising of gamma-irradiated larvae of Drosophila melanogaster on an ethanol-containing medium resulted in decreased mutation frequency in the wing somatic mutation and recombination test. This decrease in mutagenicity was mainly caused by the reduced recombination frequency. In lines with high activity of cytochrome P450, ethanol did not exhibit the radioprotective effect. Frequency of spontaneous mutations was significantly different in reciprocal crosses, whereas frequency of induced somatic mutations did not depend on the cross direction. Addition of 10% ethanol to the medium did not affect spontaneous mutation frequency.