FB2026_02 , released June 18, 2026
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Citation
Grushko, T., Rantanen, M., Portin, P. (1998). Genetic evidence that Notch affects independently the development of machrochaeta and wing venation in Drosophila melanogaster.  Hereditas 129(3): 251--257.
FlyBase ID
FBrf0108192
Publication Type
Research paper
Abstract
Temperature sensitive experiments on the interaction of Abruptex mutations of the Notch locus and Enhancer of split indicate that the effect of temperature on the development of macrochaeta and wing venation is different. This suggest that Notch affects the development of macrochaeta and wing venation in different and independent ways being in accordance with the proposition that the signal pathway from the Notch receptor at the cell membrane to Enhancer of split complex in the nucleus is different in the case of the development of macrochaeta and wing venation. The Abruptex mutations as gain-of-function mutations of the Notch locus cannot rescue the Enhancer of split phenotype.
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    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Hereditas
    Title
    Hereditas
    Publication Year
    1920-
    ISBN/ISSN
    0018-0661
    Data From Reference
    Alleles (4)
    Genes (2)