FB2026_03 , released September 17, 2026
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Gelbart, W. (2000.4.17). Smox - Sad merge - How Sad. 
FlyBase ID
FBrf0128162
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Personal communication to FlyBase
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Sad (aka Sisters against dpp; FBgn0024304) and Smox (aka Smad on X;
FBgn0025800) should be merged. Both names come from the Andrew
lab. While Sad has historic precedence based on a pc and on a
fly meeting abstract, I spoke with Debbie before she published her
paper that included Smox and we agreed that Sad was inappropriate
because (a) there was no evidence of a genetic interaction of any
kind with dpp and hence, Sad would be misleading, and (b) the
sequence similarity of the gene to vertebrate Smad2 suggests that
it is more likely to be involved in the fly's activin pathway(s)
than in its dpp/BMP pathways.
Hence, I strongly feel that Smox should be the merged name. I
have cc'd Debbie so that she can confirm/disagree.
Bill
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    English
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