Subject: (Fwd) fruitless
Priority: normal
.
Dear Gillian
I have more information on possible fruitless alternative splice
forms.
Comparing melanogaster with the Hawaiian species heteroneura
(AH009210 and silvestris (AH009214).
There is an exon within the transcript CG7689 which is an
alternative 3' end of fru in the Hawaiian species (see Gene
2462000 143-149). This sequence is conserved in melanogaster
as follows:
The exon is position 46583 to 45996 (complimentary AE003722)
and would be spliced from position 47113. Stop codon is at 45998
to 45996
The additional peptide seq is attached below
VKKSEAFLGSTGNKSMHQMLLHQAVEAQLKSFQLHYQNEGLDSA
MHRLLAQQQQHQEQQQQHQQQPHHSLGKSQSPAIPS
GSAGGSSRKSGRFRANWLYQFEWLQYDERANTMFCRHCRKWS
GELADIRTSFVEGNSNFRLEIVNHHNKCKSHRMCYERE
LQEQQQHPMPSGSAGGSSKRRSPEIITINVGKNSA
sincerely
Terry
Dr Terence Davis
Department of Pathology
University of Wales College of Medicine