Subject: Helping FlyBase: ADRC-10778
Dear Susan,
We are currently curating the abstracts for the upcoming 42nd
(Washington, D.C.) Annual Drosophila Research Conference, for FlyBase.
I am writing in connection with your abstract:
'E(Elp)24D, an EGF-receptor inhibitor, is essential for R8 patterning.'
You mention a gene that is new to FlyBase, E(Elp)24D. Do you know
which of the Genome Project CG annotations your gene corresponds to?
All the CGs have corresponding gene records in FlyBase already and we
don't like to make duplicate records for what is actually the same gene
unless we can't avoid it. If your gene does not correspond to a CG
then perhaps you could tell me its map location, as this is valuable
information for the genome annotation project.
Thank you for your help,
with best wishes,
Rachel.
Subject: Re: Helping FlyBase: ADRC-10778
Dear Rachel,
E(Elp)24D is echinoid, according to a recent paper (Bai JM, Chiu WH, Wang
JC, Tzeng TH, Perrimon N, Hsu JC 'The cell adhesion molecule Echinoid
defines a new pathway that antagonizes the Drosophila EGF receptor
signaling pathway'. Development 2001;128(4):591-601). It corresponds to est
GM09285, among others, and, as it is spread out over quite a distance on
the chromosome, matches several CG-annotated genes (CG12676, CG16842,
CG15424).
Hope this is helpful,
Cheers,
Susan