Subject: Helping FlyBase: ADRC-10921
Dear David,
We are currently curating the abstracts for the upcoming 42nd
(Washington, D.C.) Annual Drosophila Research Conference, for FlyBase.
I am writing in connection with your abstract:
'ectopic margin (ema) is required for refinement of Notch activity at the D/V
boundary of the wing.'
You mention a gene that is new to FlyBase, ema. Do you know which of the
Genome Project CG annotations your gene corresponds to? All the CGs
have corresponding gene records in FlyBase already and we don't like to
make duplicate records for what is actually the same gene unless we
can't avoid it. If your gene does not correspond to a CG then perhaps
you could tell me its map location, as this is valuable information for
the genome annotation project. Also, if the P insertions are from the
BDGP gene disruption projects then I would be grateful if you could let
me know the identifier numbers, so that I can keep all the relevent
bits and pieces in FlyBase tied together.
Thank you for your help,
with best wishes,
Rachel.
Subject: Re: Helping FlyBase: ADRC-10921
Rachel
ema maps to 100F, l(3)03429. This maps in the middle of the PTB
transcription unit but we are still working on the experiments to show
that ema encodes PTB.
The PTB trascription unit is complex based on EST and cDNA sequences and
it includes CG2094 and CG2290. Again, we have not shown that PTB is
disrupted by ema alleles but we do know that l(3)03429 is an allele of
ema.
Contact me for any clarifiaction,
David
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David A. Dansereau, Ph.D. candidate
Molecular Biology and Genetics, University of Alberta
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