Le Goff, G., Bride, J.M., Cuany, A., Berge, J.B., Amichot, M. (2001). The sibling species Drosophila melanogaster and Drosophila simulans differ in the expression profile of glutathione S-transferases.  Comp. Biochem. Physiol. B, Biochem. Mol. Biol. 129(4): 837--841.

FBrf0136830

Research paper

Two major forms of glutathione S-transferase are known in Drosophila melanogaster: GST D and GST 2. In the present paper we report the existence of a third major form of glutathione S-transferase in Drosophila simulans. Induction with phenobarbital revealed a different regulation of GST between these species. Despite the fact that these two species are closely related, there was a difference in the expression profile of the enzyme implicated in the detoxification system, suggesting variations in capacity to suit their environment.