Subject: Re: FlyBase query: EDRC2001: H7
Dear Gillian Millburn,
Identification of Dfoxo represents a continuation of my studies of
apoptosis and cell survival signaling with an emphasis on the akt pathway
(see Staveley et al., 1998. Genetic analysis of protein kinase B (AKT) in
Drosophila. Curr Biol. 1998 May 7;8(10):599-602). The foxo subfamily
(forkhead-box subclass 'o') of transcription factors (formerly FKHR,
FKHRL1 and AFX) possess three potential akt phosphorylation sites. Dfoxo
corresponds, in part, to CG3143. The first few exons of CG3143 are
correct but the 3' end of the gene was misidentified. I intend to submit
the correct sequence to NCBI within the next few months depending upon
time constraints. If you wish, I will be happy to contact you when I do.
yours,
Brian E. Staveley
On Thu, 23 Aug 2001, Gillian Millburn wrote:
> Dear Dr. Staveley,
>
> I am curating your abstract for the upcoming European Drosophila
> conference in Edinburgh, for FlyBase.
>
> I am writing in connection with your abstract:
>
> H7 'Analysis of foxo in Drosophila melanogaster.'
>
> You mention a gene that is new to FlyBase, 'Dfoxo'.
>
> Do you know which of the Genome Project CG annotations your gene
> corresponds to? All the CGs have corresponding gene records in FlyBase
> already and we don't like to make duplicate records for what is
> actually the same gene unless we can't avoid it.
>
> Any information you give me will be curated as a personal communication
> from you to FlyBase,
>
> Thank you for your help,
>
> with best wishes,
>
> Gillian
>
> \--------------------------------------------------------------
> Gillian Millburn.
>
> FlyBase (Cambridge),
> \--------------------------------------------------------------
>