Subject: Helping FlyBase: ADRC-10447
Dear Joaquim,
We are currently curating the abstracts for the upcoming 43rd
(San Diego) Annual Drosophila Research Conference, for FlyBase.
I am writing in connection with your abstract:
'Characterization of a new gene involved in the development of the proboscis.'
You mention a gene that is new to FlyBase, boca. Do you know which of the
Genome Project CG annotations your gene corresponds to? All the CGs
have corresponding gene records in FlyBase already and we don't like to
make duplicate records for what is actually the same gene unless we
can't avoid it. If your gene does not correspond to a CG then perhaps
you could tell me its map location, as this is valuable information for
the genome annotation project.
Thank you very much for your help,
with best wishes,
Rachel.
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Rachel Drysdale, Ph.D.
FlyBase (Cambridge),
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Subject: Re: Helping FlyBase: ADRC-10447
Dear Rachel Drysdale,
I am writing to you regarding your request for information about the
newly characterized gene boca, that we will present in the next ADRC
in San Diego.
boca corresponds to CG1364 but please, note the FlyBase error report
for CG1364 from Bernadette Holdener (FBrf0131065) that suggested
CG1364 is in fact a merge of two independent genes. We agree with her
interpretation. boca corresponds to the 5' moiety of CG1364.
Moreover, we sequenced CG1364 transcription unit in the stock
l(2)43Ea and found a point mutation inside the ORF, suggesting that
CG1364 and l(2)43Ea are in fact the same gene.
I hope this information will help avoid duplications during the
annotation of Drosophila Genome. Please, do not hesitate to contact
me if you need additional information.
Best wishes,
Dr. Joaquim Culi
Joaquim Culi
Dept. of Biochemistry and Molecular Biophysics.
Columbia University
701 West 168th Street, HHSC 0602
New York, NY 10032