Subject: AP-47SAE-10 and AP-47SHE-11 The following information was provided by Annette Parks of Exelixis, Inc. (5/04). AP-47SAE-10 and AP-47SHE-11 were both induced with EMS. AP-47SAE-10 is a S366N change. AP-47SHE-11 is a 37 nucleotide deletion resulting in the deletion of amino acids 146 to 158 and a frameshift.