FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\AP-1μSAE-10
Open Close
General Information
Symbol
Dmel\AP-1μSAE-10
Species
D. melanogaster
Name
FlyBase ID
FBal0157516
Feature type
allele
Associated gene
Dmel\AP-1μ
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Benhra et al., 2011)
Mutagen
ethyl methanesulfonate
(Mahoney et al., 2006, Parks, 2004.5.6)
Progenitor genotype
Cytology
Description

Amino acid replacement: S366N.

(Mahoney et al., 2006, Parks, 2004.5.6)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:9,558,094..9,558,094 [-]
Nucleotide change:

G9558094A

Amino acid change:

S366N | AP-1mu-PA

Reported amino acid change:

S366N

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Mahoney et al., 2006, Parks, 2004.5.6)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      AP-1μSAE-10 is an enhancer of visible phenotype of Psn9/Psn143

      (Mahoney et al., 2006)
      NOT Enhancer of
      Statement
      Reference

      AP-47[+]/AP-1μSAE-10 is a non-enhancer of abnormal neuroanatomy | larval stage phenotype of NakRNAi.UAS, Scer\GAL4109(2)80

      (Yang et al., 2011)
      Other
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      AP-1μSAE-10 is an enhancer of eye phenotype of Psn9/Psn143

      (Mahoney et al., 2006)
      NOT Enhancer of
      Statement
      Reference

      AP-47[+]/AP-1μSAE-10 is a non-enhancer of dendritic arborizing neuron | larval stage phenotype of NakRNAi.UAS, Scer\GAL4109(2)80

      (Yang et al., 2011)

      AP-47[+]/AP-1μSAE-10 is a non-enhancer of dendrite | larval stage phenotype of NakRNAi.UAS, Scer\GAL4109(2)80

      (Yang et al., 2011)
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The reduction in the number of dendritic endpoints of dorsal dendritic arborisation neurons which is seen in larvae expressing NakdsRNA.Scer\UAS under the control of Scer\GAL4109(2)80 is not enhanced by AP-47SAE-10/+.

      (Yang et al., 2011)

      AP-47SAE-10 Psn9/Psn143 flies show wing vein thickening.

      AP-47SAE-10/AP-47SHE-11 Psn9/Psn143 flies have dorsal and ventral wing notching, enhanced wing vein thickening and show loss of notal microchaetae.

      (Mahoney et al., 2006)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      AP-1μSAE-10
      AP-47SAE-10
      AP-47SAE10
      (Benhra et al., 2011)
      AP47SAE-10
      (Yang et al., 2011)
      SAE-10
      (Mahoney et al., 2006)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)