Subject: Helping FlyBase: ADRC-50458
Dear Nicolas,
We are currently curating the abstracts for the upcoming 46th
(San Diego) Annual Drosophila Research Conference, for FlyBase.
I am writing in connection with your abstract:
Spindle orientation during asymmetric division of the sensory organ precursor
cell.
You mention a gene symbol that is apparently new to FlyBase, RIC-8.
Can youtell us what RIC stands for? Also do you know which of the
Genome Project CG annotations your gene corresponds to? All the CGs
have corresponding gene records in FlyBase already and we don't like to
make duplicate records for what is actually the same gene unless we
can't avoid it. The CG symbols become synonyms when an annotation is
named with a more descriptive or functional name.
With best wishes,
Rachel.
Subject: Re: Helping FlyBase: ADRC-50458
Dear Rachel,
We refer to our gene as ric8 (we suppressed the '-') in reference to the name
used for its homolog in C.elegans (Afshar K. et al. Cell 119, 2004;
Couwenbergs C. et al., Current Biology, 14, 2004). Ric-8 is also known as
synembryn.
In Drosophila, we found two CG with good homology to C.elegans ric-8.
They are CG15797 (gene l(1)G0397) and CG15910. So far we decided to refer to
CG15797 as ric8a and CG15910 as ric8b, eventhough CG15910 is likely to be a
pseudogene.
So far, none of this is published, and I know other groups are working on the
same genes. I don't know what they have decided regarding gene names, although
I think they will refer to CG15797 as ric8.
I hope this answers your question. Please feel free to ask for more details if
you need.
With best wishes,
Nicolas