FB2026_03 , released September 17, 2026
Reference Report
Open Close
Reference
Citation
Rice, S.E., Gelfand, V.I. (2006). Paradigm lost: milton connects kinesin heavy chain to miro on mitochondria.  J. Cell Biol. 173(4): 459--461.
FlyBase ID
FBrf0194320
Publication Type
Note
Abstract
The kinesin motor typically binds to cargo through its light chains. In this issue Glater et al. demonstrate a new type of linkage through the adapter protein, milton, and the mitochondrial membrane GTPase, miro. This is an important result because it represents a new mechanism of cargo binding and because miro's ability to bind GTP and calcium suggests that it is involved in the regulation of mitochondrial transport.
PubMed ID
PubMed Central ID
PMC2063855 (PMC) (EuropePMC)
Related Publication(s)
Research paper

Axonal transport of mitochondria requires milton to recruit kinesin heavy chain and is light chain independent.
Glater et al., 2006, J. Cell Biol. 173(4): 545--557 [FBrf0194133]

Associated Information
Comments
Associated Files
Other Information
Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    J. Cell Biol.
    Title
    Journal of Cell Biology
    Publication Year
    1966-
    ISBN/ISSN
    0021-9525
    Data From Reference