FB2026_02 , released June 18, 2026
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Heitzler, P. (2006.8.9). A description of the generation of the alleles pnr[VE12] and pnr[VE13]. 
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FBrf0198695
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Personal communication to FlyBase
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Subject: Re: pnrVE12
pnrVE12 and pnrVE13 require a little communication (Schaal, 
Biryukova & Heitzler) to flybase since they did not appear in 
previous literature.
They were EMS induced and represent new null alleles of pnr, found in 
a ChipE/+ background as dominant enhancers of ChipE. In both cases 
they encode a severely truncated protein due to premature stop codon.
VE12: R98*. R98 (cga) becomes stop (tga). VE12 encodes a 97 aa isoform A 
protein and a 45 aa isoform B protein. VE13: Q113*. Q113 (cag) becomes stop (tag). VE13 encodes a 112 aa isoform A protein and a 60 aa isoform B protein.  The molecular characterization has been performed (pcr) by Aurelie Schaal during her DUT probationary period in my lab. Both mutants show the severe embryonic dorsal hole phenotype.
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    English
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