None of the polypeptides share 100% sequence identity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Chi using the Feature Mapper tool.
Chi protein is detected in embryonic and larval cell nuclei. Staining is also detected along salivary gland chromosomes.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Chi in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Gene expression is increased in response to the presence of two copies of Scer\GAL4hs.PB.
S2 cells treated with dsRNA generated against this gene show reduced phagocytosis of Candida albicans compared to untreated cells.
Mutations in Chi show strong genetic interaction with ap. In spite of its generalized expression, lack of Chi function in genetic mosaics produces specific phenotypes identical to the phenotype of ap mutant clones; i.e., dorsoventral transformation, generation of new wing margins and wing outgrowths. Overexpression of Chi produces a new wing margin, but only where ap is expressed.
Gene isolated in a screen of the second chromosome identifying mutants affecting disc morphology.
Chi cooperates with different LIM domain proteins and other factors to structurally support enhancer-promoter interactions.