- Tools
- Downloads
- Links
- Community
- About
- Help
FB2026_01
,
released March 12, 2026
dLdb, Ldb
transcription factor - enhancer facilitator - functions at enhancers to bring together diverse transcriptional factors and form higher order activation complexes; or, in some cases, it may block formation of such complexes - Chip-mediated partnerships of the homeodomain proteins Bar and Aristaless with the LIM-HOM proteins Apterous and Lim1 regulate distal leg development
Please see the JBrowse view of Dmel\Chi for information on other features
To submit a correction to a gene model please use the Contact FlyBase form
AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.46
Tissue-specific extension of 3' UTRs observed during later stages (FBrf0218523, FBrf0219848); all variants may not be annotated
2.2 (northern blot)
None of the polypeptides share 100% sequence identity.
577 (aa)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Chi using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Comment: maternally deposited
Chi transcript is expressed in all developmental stages. Expression in early embryos (0-30 min) is tenfold higher than in later developmental stages.
Chi protein is detected in embryonic and larval cell nuclei. Staining is also detected along salivary gland chromosomes.
Chi is expressed in many cells surrounding the antennal lobe at 18hrs APF.
JBrowse - Visual display of RNA-Seq signals
View Dmel\Chi in JBrowse2-106
2-109.9
2-107
2-106.8
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
monoclonal
polyclonal
Gene expression is increased in response to the presence of two copies of Scer\GAL4hs.PB.
S2 cells treated with dsRNA generated against this gene show reduced phagocytosis of Candida albicans compared to untreated cells.
Chi has a role in segmentation.
Mutations in Chi show strong genetic interaction with ap. In spite of its generalized expression, lack of Chi function in genetic mosaics produces specific phenotypes identical to the phenotype of ap mutant clones; i.e., dorsoventral transformation, generation of new wing margins and wing outgrowths. Overexpression of Chi produces a new wing margin, but only where ap is expressed.
Gene isolated in a screen of the second chromosome identifying mutants affecting disc morphology.
Chi cooperates with different LIM domain proteins and other factors to structurally support enhancer-promoter interactions.
Source for merge of: Chi Ldb
"Ldb" may correspond to "Chi".
Source for identity of: Chi CG3924
