FlyBase Allele Report: Dmel\Chi[ΔDD.UAS.Tag:MYC]

General Information

Symbol

Dmel\Chi^{ΔDD.UAS.Tag:MYC}

Species

D. melanogaster

Name

FlyBase ID

FBal0103087

Feature type

allele

Associated gene

Dmel\Chi

Associated Insertion(s)

Carried in Construct

P{UAS-Chi.ΔDD}

Also Known As

UAS-ChipΔDD

Key Links

Transgenic product class

inframe_deletion

(van Meyel et al., 1999)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

inframe_deletion

(van Meyel et al., 1999)

Mutagen

in vitro construct

(van Meyel et al., 1999)

Progenitor genotype

Chi^{FL.UAS.Tag:MYC}

(van Meyel et al., 1999)

Carried in construct

P{UAS-Chi.ΔDD}

Cytology

Description

Deletion of amino acids 221 to 376 (the predicted dimerisation domain).

(van Meyel et al., 1999)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Chi

Tagged with

Tag:MYC

epitope tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal eclosion, with Scer\GAL4^CCAP.PP

(Hari et al., 2008)

visible, with Scer\GAL4^ap-md544

(van Meyel et al., 1999)

Phenotype Manifest In

eye-antennal disc | somatic clone | third instar larval stage, with Chi^45F, Scer\GAL4^αTub84B.PL

(Roignant et al., 2010)

photoreceptor neuron | somatic clone | third instar larval stage, with Chi^45F, Scer\GAL4^αTub84B.PL

(Roignant et al., 2010)

wing, with Scer\GAL4^ap-md544

(van Meyel et al., 1999)

wing, with Scer\GAL4^CCAP.PP

(Hari et al., 2008)

Detailed Description

Statement

Reference

Chi^45F mutant clones expressing Scer\GAL4^αTub84B.PL>Chi^{ΔDD.Scer\UAS.T:Hsap\MYC} still differentiate ectopic photoreceptors in the ventral anterior eye disc.

(Roignant et al., 2010)

Expression of Chi^{ΔDD.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^Ccap.PP gives rise to flies that do not open their wings after eclosion. This phenotype is fully penetrant at 25[o]C.

(Hari et al., 2008)

Flies expressing Chi^{ΔDD.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^ap-md544 show severe wing defects that mimic those of ap null mutants.

(van Meyel et al., 1999)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Chi^{ΔDD.UAS.Tag:MYC}, Scer\GAL4^ap-md544 has visible phenotype, suppressible by ap^UAS.cOa, Scer\GAL4^ap-md544

(van Meyel et al., 1999)

Suppressor of

Statement

Reference

Chi^{ΔDD.UAS.Tag:MYC}, Scer\GAL4^vg.PU is a suppressor of visible | adult stage phenotype of Awh^UAS.cUa, Scer\GAL4^vg.PU

(Singh et al., 2025)

Chi^{ΔDD.UAS.Tag:MYC}, Scer\GAL4^vg.PU is a suppressor of decreased size | adult stage phenotype of Awh^UAS.cUa, Scer\GAL4^vg.PU

(Singh et al., 2025)

Phenotype Manifest In

Suppressed by

Statement

Reference

Chi^{ΔDD.UAS.Tag:MYC}, Scer\GAL4^ap-md544 has wing phenotype, suppressible by ap^UAS.cOa, Scer\GAL4^ap-md544

(van Meyel et al., 1999)

Suppressor of

Statement

Reference

Chi^{ΔDD.UAS.Tag:MYC}, Scer\GAL4^vg.PU is a suppressor of wing phenotype of Awh^UAS.cUa, Scer\GAL4^vg.PU

(Singh et al., 2025)

Additional Comments

Genetic Interactions

Statement

Reference

The phenotype of flies expressing Chi^{ΔDD.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^ap-md544 is partially suppressed by co-expression of ap^Scer\UAS.cOa.

(van Meyel et al., 1999)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to rescue

Scer\GAL4^αTub84B.PL/Chi^{ΔDD.UAS.Tag:MYC} fails to rescue Chi^45F

(Roignant et al., 2010)

Scer\GAL4^ap-md544/Chi^{ΔDD.UAS.Tag:MYC} fails to rescue Chi^e5.5

(van Meyel et al., 2000)

Comments

Chi^45F mutant clones expressing Scer\GAL4^αTub84B.PL>Chi^{ΔDD.Scer\UAS.T:Hsap\MYC} still differentiate ectopic photoreceptors in the ventral anterior eye disc.

(Roignant et al., 2010)

Chi^{ΔDD.Scer\UAS.T:Hsap\MYC} fails to rescue the interneuron pathfinding errors seen in Chi^e5.5 embryos when expressed under the control of Scer\GAL4^ap-md544.

(van Meyel et al., 2000)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Chi^{ΔDD.Scer\UAS.T:Hsap\MYC}

Chi^{ΔDD.UAS.Tag:MYC}

Name Synonyms

Secondary FlyBase IDs

References (8)

Report Sections

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