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General Information
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| Term |
transcription coregulator activity |
ID (Ontology) |
GO:0003712 (Gene Ontology) |
| Definition |
A transcription regulator activity that modulates the transcription of specific gene sets via binding to a DNA-binding transcription factor at a specific genomic locus, either on its own or as part of a complex. Coregulators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators.[ PubMed:10213677 PubMed:16858867 PubMed:24203923 PubMed:25957681 ] |
| Also Known As |
"transcription cofactor activity" ; "transcription coreceptor activity" ; "transcriptional co-regulator" |
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Links to External Ontologies
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QuickGO data AmiGO data
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Annotations
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Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
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| Data Class | Field | Records |
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| Genes (FBgn) | GO_CELLULAR_COMPONENT | 3 | | Genes (FBgn) | GO_MOLECULAR_FUNCTION | 71 |
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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| Full annotation statements | Relevant FlyBase reports |
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| Gene Groups | Genes |
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transcription coregulator activity (all annotations which use CV term, excluding "NOT" statements) | 2 | 71 | contributes_to | transcription coregulator activity | -- | 6 | enables | transcription coregulator activity | -- | 68 |
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Relationships
