FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
tup, Chi
FlyBase ID
FBig0000102120
Interaction Network
Interactions Browser links
tup network
Chi network
Reported Interactions
FBrf0190092-1.coIP.WB
Reference
Biryukova and Heitzler, 2005
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-unspecified
Participants
Corresponds to
Reported as
Role
Note
tup 

Isl

bait

FLAG tag

Chi 

Chip

prey

Myc tag

Chi 
Chi 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Chi 
LID domain
necessary binding region
aa 484-515
Chi 
LID domain residue 504
mutation disrupting interaction
aa 504

R504W

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Biryukova and Heitzler, 2005)
FBrf0227292-300.TFIN
Reference
Rhee et al., 2014
Description
physical association
Assay
Collection
TF_Interaction_Network-2
Source/Stage
Cell line used
S2R+
Participants
Corresponds to
Reported as
Role
Note
tup 

FBgn0003896

unspecified role
tup 

FBgn0003896

unspecified role
tup 

FBgn0003896

unspecified role
Chi 

FBgn0013764

unspecified role
Chi 

FBgn0013764

unspecified role
Chi 

FBgn0013764

unspecified role
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of S2R+ cell line; proteins produced from transfected construct or endogenous gene.

(Rhee et al., 2014)

HGScore = 14.902503

(Rhee et al., 2014)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (2)