McDaniel, I.E., Lee, J.M., Berger, M.S., Hanagami, C.K., Armstrong, J.A. (2008). Investigations of CHD1 function in transcription and development of Drosophila melanogaster. Genetics 178(1): 583--587.
FlyBase ID
FBrf0202628
Publication Type
Research paper
Abstract
In this report we describe chd1 mutant alleles and show that the CHD1 chromatin-remodeling factor is important for wing development and fertility. While CHD1 colocalizes with elongating RNA polymerase II (Pol II) on polytene chromosomes, elongating Pol II can persist on chromatin in the absence of CHD1. These results clarify the roles of chromatin remodelers in transcription and provide novel insights into CHD1 function.
