FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
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Negre, N., Bild, N., Brown, C.D., Shah, P.K., Kheradpour, P., Morrison, C.A., Kellis, M., White, K.P. (2010.2.22). Class I and Class II insulator elements. 
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FBrf0210089
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Personal communication to FlyBase
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Insulator binding data was processed with Model based Analysis Tiling-arrays (MAT) software (Johnson et al., 2006, Proc Natl Acad Sci USA  103:12457-12462 ). We ran paired MAT analysis with MaxGap of 500, MinProbe of 10, and a Bandwidth of 250. We report here the peaks found by MAT at 1% FDR.
Class I was computed as binding sites at 1% FDR for at least 2 components among CP190, BEAF32 and CTCF, with overlap by less than 250bp between their peak center (mid-peak) location.
Class II is defined by Su(Hw) binding sites only; using 2 independent antibodies for Su(Hw), we computed all peaks for both experiments that overlap by less than 250 bp.
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Related Publication(s)
Research paper

A comprehensive map of insulator elements for the Drosophila genome.
Nègre et al., 2010, PLoS Genet. 6(1): e1000814 [FBrf0209760]

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File date: 2010.2.22 ; File size: 108798 ; File format: bed ; File name: Negre_ClassI_insulators.bed
File date: 2010.2.22 ; File size: 66728 ; File format: bed ; File name: Negre_ClassII_insulators.bed
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    English
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