Chen, X., Lee, K.A., Ha, E.M., Lee, K.M., Seo, Y.Y., Choi, H.K., Kim, H.N., Kim, M.J., Cho, C.S., Lee, S.Y., Lee, W.J., Yoon, J. (2011). A specific and sensitive method for detection of hypochlorous acid for the imaging of microbe-induced HOCl production.  Chem. Commun. (Camb.) 47(15): 4373--4375.

FBrf0214439

Research paper

A specific and sensitive fluorescence-based method was developed for the imaging of microbe-induced HOCl production. Furthermore, we demonstrate dual oxidase (DUOX)-mediated HOCl generation in the mucosa of live animals providing a novel insight into mucosal innate immunity.