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Citation
Joshi, S.S., Cheong, H., Meller, V.H. (2014). A strategy for generation and balancing of autosome: Y chromosome translocations.  Fly 8(1): 58--62.
FlyBase ID
FBrf0224440
Publication Type
Research paper
Abstract

We describe a method for generation and maintenance of translocations that move large autosomal segments onto the Y chromosome. Using this strategy we produced ( 2;Y) translocations that relocate between 1.5 and 4.8 Mb of the 2(nd) chromosome.. All translocations were easily balanced over a male-specific lethal 1 (msl-1) mutant chromosome. Both halves of the translocation carry visible markers, as well as P-element ends that enable molecular confirmation. Halves of these translocations can be separated to produce offspring with duplications and with lethal second chromosome deficiencies . Such large deficiencies are otherwise tedious to generate and maintain.

PubMed ID
PubMed Central ID
PMC3974896 (PMC) (EuropePMC)
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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Fly
    Title
    Fly
    Publication Year
    2007-
    ISBN/ISSN
    1933-6934 1933-6942
    Data From Reference
    Aberrations (6)
    Alleles (2)
    Balancers (1)
    Insertions (4)
    Transgenic Constructs (1)