Yang, Z., Pillai, R.S. (2014). Fly piRNA biogenesis: tap dancing with Tej. BMC Biol. 12(): 77.
FlyBase ID
FBrf0226876
Publication Type
Note
Abstract
Piwi-interacting RNAs (piRNAs) protect animal germlines from the deleterious effects of transposon activity. Unlike other small RNA classes like microRNAs (miRNAs) and small interfering RNAs (siRNAs), an exceptionally large number of factors are implicated in the biogenesis of piRNAs. Kai et al. have now added another one to this growing list, which we discuss in the overall context of our current knowledge of the piRNA biogenesis pathway in the Drosophila ovarian germline. See research article: http://www.biomedcentral.com/1741-7007/12/61.
The Tudor domain protein Tapas, a homolog of the vertebrate Tdrd7, functions in the piRNA pathway to regulate retrotransposons in germline of Drosophila melanogaster.
Patil et al., 2014, BMC Biol. 12(1): 61 [FBrf0227959]
