Langlois, C.R., Wollert, T. (2016). Digesting cytotoxic stressors - an unconventional mechanism to induce autophagy.  FEBS J. 283(21): 3886--3888.

FBrf0234124

Note

Autophagy is an essential and fundamental pathway that clears unwanted or damaged material from the cell. Initiation of autophagy was previously shown to be dependent on the Ulk1/2 kinase complex. In this issue of The FEBS Journal, Braden and Neufeld investigated the Ulk3 homolog in Drosophila, and proposed a novel, Ulk1/2 independent pathway for autophagy initiation.