Kostyuchenko, M.V., Golovnin, A.K., Georgiev, P.G., Melnikova, L.S. (2018). The Role of GC-Rich Sequences from the Promoter Region of the Drosophila melanogaster yellow Gene in the Enhancer-Dependent Activation of Transcription.  Dokl. Biochem. Biophys. 482(1): 255--260.

FBrf0240556

Research paper

It is shown that mutations in two GC-rich sequences (GC-boxes) from the promoter region of the yellow gene during enhancer-dependent transcription activation do not affect the basal level of the yellow gene transcription but destabilize the interaction between the enhancers and the promoter.