Lilienthal, A.J., Parida, M., Manak, J.R. (2022). Characterization of prickle isoform-specific pk pk1 and pk sple1 mutations in Drosophila melanogaster. MicroPubl Biol 2022(): .
FlyBase ID
FBrf0254943
Publication Type
Research paper
Abstract
We used paired-end next generation sequencing (NGS) to characterize the classic isoform-specific pk pk1 and pk sple1 mutations of the prickle gene in Drosophila melanogaster . Here we provide evidence that these previously reported null mutations are caused by either a tirant transposon insertion into the 5' UTR of pk pk1 or a premature stop codon in the second exon of pk sple1 . Additional likely benign missense mutations were identified in both mutant isoforms.
