Gordon, K., Gonzales, P., Lee, C., Marcin, J., Takashima, Y., Lazzaro, B., Wolfner, M. (2023). Drosophila Arc1 is not required for male fertility or sperm competition success. MicroPubl Biol 2023(): .
FlyBase ID
FBrf0258325
Publication Type
Research paper
Abstract
Activity-regulated cytoskeleton associated protein (Arc1), which is required for synaptic plasticity and metabolism in Drosophila , self-assembles into capsid-like structures that transport mRNAs in extracellular vesicles. In addition to expression in the brain and nervous system, Arc1 is expressed in the male accessory glands, an endothelial tissue that produces male seminal proteins and exosomes that impact male fertility. We thus hypothesized that Arc1 might impact male fertility. We measured the fertility, mating latency, mating duration, and sperm competition performance of Arc1 males relative to controls and found no evidence that Arc1 is required for any of these measures of male fertility.
