The following information accompanied stocks donated to the Bloomington Drosophila Stock Center by Tian Xu, Yale University School of Medicine.
pbltum1 Harbors an EMS induced mutation P596L.
pbltum2 Harbors an EMS induced mutation A755T.
pbltum3 Harbors an EMS induced mutation causing frame-shift at K761 followed by 13 random amino acid residues.
P{UASp-pbl.tumH.FLAG} Expresses a mutant pbl with a single amino acid substitution T758P under UAS control. This change is equivalent to a T802P change in the human ECT2 gene (a variant identified in human cancers). The coding sequence is tagged with FLAG.
P{UASp-pbl.tum3.FLAG} Expresses a mutant pbl lacking the C-terminal 92 amino acid residues (corresponds to pbltum3). The coding sequence is tagged with FLAG.
P{UASp-pbl.tumH.FLAG}3A1 is a third chromosome insertion.
P{UASp-pbl.tum3.FLAG}4A1 is a third chromosome insertion.