FB2026_02 , released June 18, 2026
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Ahmed, Y. (2024.1.29). Molecular characterization of Wdr20, Uaf1, and Usp12-46 mutations. 
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FBrf0258705
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Wdr2034 – The sequence of the insertion is ACATTGTACG.
Wdr2033 - The sequence of the insertion is CT. 
Uaf13 – The sequence of the insertion is CATAGTACTTTG. 
Usp12-461 – The deletion starts at genomic position 22775329. (junction sequence 5’ of deletion: GATCAATCACATCAATGAGATC, junction sequence 3’ of deletion: GGCTACATACTGTTCTATCAGTCGCGG) 
Usp12-4621 : The 5 bp deletion starts at genomic position 22775157.  
 (junction sequence 5’ of 5 bp deletion: CAAGAGGCCCAAGGAGACGCTGCTGTC, 
junction sequence 3’ of 5 bp deletion:  TGGCGGATCTGTTCTACAGCATTG) 
 The 3 bp deletion starts at genomic position 22775326. 
(junction sequence 5’ of 3 bp deletion: CTTTCTGATCAATCACATCAATGAG, 
junction sequence 3’ of 3 bp deletion:  ATACTGGCCGAACGGAATGCAGGGCC)
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Related Publication(s)
Research paper

The USP46 deubiquitylase complex increases Wingless/Wnt signaling strength by stabilizing Arrow/LRP6.
Spencer et al., 2023, Nat. Commun. 14(1): 6174 [FBrf0257735]

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