FB2026_02 , released June 18, 2026
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Citation
Renault, A.D. (2024). Optogenetic control of Drosophila neurons: a laboratory practical for undergraduates and outreach.  J. Microbiol. Biol. Educ. 25(3): e0008624.
FlyBase ID
FBrf0261190
Publication Type
Research paper
Abstract
Teaching aspects of neuroscience to large undergraduate classes can be difficult in terms of the cost of equipment involved such as microscopes and electrophysiology equipment, the time taken to master techniques such as dissection or intracellular recording, and ethical concerns when using vertebrates. Here, I describe a practical that uses behavioral readouts and optogenetics on Drosophila that can be implemented with minimal cost as well as reduced ethical concerns and uses mostly observational techniques. The practical can be used to teach aspects of genetics and the tools for manipulating neuronal activity for ascribing neuronal function. The practical can be customized to fit different undergraduate levels and learning objectives.
PubMed ID
PubMed Central ID
PMC11636384 (PMC) (EuropePMC)
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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    J. Microbiol. Biol. Educ.
    Title
    Journal of microbiology & biology education : JMBE
    ISBN/ISSN
    1935-7877 1935-7885
    Data From Reference
    Genes (3)